CV

Current position : Researcher – Assistant Professor (CR1 CNRS, HDR),

I was appointed in 2015 as permanent CNRS researcher in the VirPath Team (Pr Bruno Lina/Dr Manuel Rosa-Calatrava), which is part of the Centre International de Recherche en Infectiologie (CIRI, INSERM U1111, CNRS UMR5308, ENS Lyon & Université Claude Bernard Lyon 1), based in Lyon, France.

Over the past 15 years, I have developed a strong expertise in the study of respiratory viruses, combining virology, molecular and cellular biology approaches, and developing experimental infection models in reconstituted human airway epithelium (HAE). 

My current research projects consist to study virus-host interactions at the level of human respiratory epithelium, with a focus on co-infections/superinfections between viruses and bacteria. Another part of my current work is dedicated to the development of innovative approaches to identify/repurpose small molecules of interest in the field of respiratory viruses based on their transcriptional signatures of infection.

These last 10 years, I was involved in several national and international collaborations, I published more that 50 manuscripts in internationally peer-reviewed journals and was involved as inventor in 12 international patents. I regularly reviews manuscripts for international journals and program grants applications and I am currently Academic Editor for Scientific Reports and Review Editor for Frontiers in Microbiology. I am also elected member of the steering committee of National Research Program “COVID-19” NRP78 of the Swiss National Science Foundation (SNSF).

I co-founded Signia Therapeutics (https://signiatherapeutics.com). SIGNIA Therapeutics proposes a breakthrough strategy to identify and repurpose rapidly, efficiently and at low cost already marketed drugs or to recycle unused drugs for new antiviral indication against several human respiratory viruses.

Previous positions

2012-2015: Postdoctoral position. VirPath lab, Lyon , France (Dr Manuel Rosa-Calatrava). Study of the functional interplay between influenza viruses and the p53 pathway. Transcriptome -based identification and repurposing of antiviral molecules.

2010-2012: Associate postdoctoral researcher. Department of Surgery and Molecular Oncology, Dundee, UK (Prof Sir David P Lane and Dr Jean-Christophe Bourdon) in collaboration with VirPath lab EA4610, Lyon, France (Dr Manuel Rosa-Calatrava). Study of the interplay between influenza viruses and the p53 pathway.

2009-2010 : Postdoctoral position. FRE CNRS-UCBL 3011, Lyon, France (Prof. Bruno Lina). Influenza and parainfluenza envelope glycoproteins.

2005-2009: Doctoral position. FRE CNRS-UCBL 3011, Lyon, France (Prof. Bruno Lina). Parainfluenza virus envelope glycoproteins: structure versus function study and development of diagnostic and therapeutic applications.

2004-2005: Master student. FRE CNRS-UCBL 3011 and National reference center for Influenza (WHO collaborating center for Influenza), Lyon, France (Prof. Bruno Lina). Characterization of naturally occurring human parainfluenza type 2 virus (hPIV-2) variants.

Nov. 2003-May 2004: Master student. Laboratoire de Microbiologie et génétique UMR 5122, Lyon, France (Prof. Raymond Portalier). Study of the gene expression in oligopeptide transport in Lactococcus lactis.